Topic of research

การศึกษา

Outcome

The vast majority of malaria vaccinology has focussed on P. falciparum and animal models. These animal models have provided fundamental insights into malaria immunity and allowed down-selection of vaccine candidates but none reproduce the human condition in endemic areas. Vaccine development in P. vivax has been relatively neglected. Vivax CHMI model in Southeast Asia, the heartland of vivax malaria, will advance vivax vaccine development to 2 major roles

  1. testing candidate vaccines to accelerate licensure among the current generation of vaccines.
  2. identifying immunological correlates of protection to guide development of the next generation of vaccines.